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Our Research Focus

Addressing the impacts of atmospheric particles on Earth's System and human health necessitates detailed physicochemical characterization at single-particle level. We aim to understand the evolution of aerosol particles in the atmosphere and their environmental implications.

As a leading research lab, Lei Laboratory is committed to advancing the knowledge and understanding of atmospheric aerosols. Our team of experts is dedicated to conducting groundbreaking research that sheds light on the complex interactions between aerosol particles and the environment. Through our innovative approach, we strive to provide valuable insights that contribute to the global effort of mitigating the effects of aerosols on human health.

Our Mission

Our mission is to provide new insights into the role of atmospheric particles in climate and environmental health. By bridging fundamental science with real-world applications, we strive to inform policies and contribute to global efforts in combating climate change.

Smoky Mountain Look Rock

Our multidisciplinary approach combines state-of-the-art experimental techniques, field measurements, and modeling to address key scientific questions. Here are our primary research areas:

01

Aerosol-Cloud Interactions

We investigate how aerosols, such as dust, pollen, and biomass burning particles, interact with clouds and influence their formation, properties, and precipitation patterns. Understanding these interactions is crucial for improving weather and climate predictions.

02

Physicochemical Properties of Aerosols

Our work focuses on characterizing the physical and chemical properties of atmospheric particles. By analyzing their size, composition, and optical properties, we aim to understand how these factors affect their role as cloud condensation nuclei (CCN) and ice-nucleating particles (INP).

03

Aerosol Mixing State

We explore the sources, composition, and health impacts of aerosols in both urban and rural environments. Our research seeks to quantify the contributions of aerosols from varying sources and atmospheric chemistry, providing insights into mitigation strategies.

04

Advanced Spectroscopic and Microscopic Techniques

Utilizing cutting-edge tools such as Optical Photothermal Infrared Spectroscopy (O-PTIR), Raman spectroscopy, Atomic Force Microscopy (AFM), Scanning Electron Microscopy Energy Dispersive X-Ray Spectroscopy (EDS), we analyze aerosols at a molecular level and elemental level to better understand their behavior and interactions in the atmosphere.

Our Ongoing Research

Aerosol-Cloud Interaction
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We investigate how atmospheric particles form cloud droplets and ice crystals, influencing clouds, precipitation, and climate.

Wildfire Smoke
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U.S. Forest Service Prescribed Fire Science Laboratory 

•2025 Jan 10th, Los Angeles fire burned over 29,053 acres, the destruction of over 2,000 buildings, and an estimated damage cost of $52 billion.​

•Global increase of extreme fires of up to 30% by 2050, and 50% by the end of the century.

We study particles generated by wildfires and agricultural burning, focusing on how burning conditions and atmospheric aging alter their chemistry and cloud-forming potential.

Biological Particles in the Atmosphere
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Pollen emissions
Look Rock Site
Lei Lab Field Work

•Annual pollen emissions estimate 47-84 Tg/year

•In peak pollen season, deciduous and evergreen trees produce 10,000 pollen grains per cubic meter

We examine how pollen and other biological particles are released, transported, and involved in cloud formation.

Microplastics and Human Health
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•Global plastic production reached 430.9 million metric tons in 2024. 

We investigate how plastic particles are released into the air and assess their potential environmental source and human-exposure implications.

Aerosol Acidity Measurement
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Aerosol acidity contributes to acid deposition, including acid rain, with important effects on ecosystems and water quality.

We develop new methods to measure aerosol acidity and investigate its effects on atmospheric chemistry, air quality, cloud formation, and acid deposition.

Instrumentation Tools

Microscopy Techniques

Scanning Electron Microscopy (SEM) Energy Dispersive X-Ray Spectroscopy (EDS)

Atomic Force Microscopy

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Individual particle SEM with elemental mapping (EDS)

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AFM Height image of secondary organic aerosols

Spectroscopy Techniques

Raman Spectroscopy

Raman

532 nm laser shooting on the sample

Microscopic Image

aerosol particles

Microscopic image of individual particles

Cutting Edge Optical Photothermal Infrared (O-PTIR) + Raman

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Ice Nucleation and Cloud Property Measurements

Temperature controlled cooling stage 

Freezing event for microdroplet (ice crystals growth)

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Cloud Condensation Nuclei Counter

209 Dabney-Buehler Hall, 1420 Circle Dr Knoxville, TN 37996

(865) 974-8746

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